| 1. Wallaert B, et al. Respir Med 1999; 93: 33–8 |
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Similar efficacy and control of nocturnal and daily asthma symptoms were obtained with Bambec 20 mg at bedtime and inhaled salmeterol 50 µg twice daily in a group of moderate to severe asthma patients with nocturnal asthma. No difference in incidence of tremor was observed between treatments.
Efficacy of Bambec: nocturnal fall in PEF
Bambec versus inhaled salmeterol
Bambec treatment consisted of 10 mg once daily for 1 week and 20 mg once daily for the next 5 weeks. Salmeterol 50 µg was given twice daily.
Adapted from Wallaert et al., 1999. |
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| 2. Crompton GK, et al. Am J Respir Crit Care Med 1999; 159: 824–8 |
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Once-daily Bambec is a convenient, effective treatment for asthma which is comparable to twice-daily inhaled salmeterol. Both treatments were well tolerated.
Bambec and salmeterol provide similar control of nocturnal asthma in patients using inhaled glucocorticosteriods
Bambec treatment consisted of 10 mg once daily for 1 week and 20 mg once daily for the next 5 weeks. Salmeterol 50 µg was given twice daily.
Adapted Crompton et al., 1999. |
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| 3. Crompton GK, et al. Am J Resp Crit Care Med 1999; 159: 824–8 |
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| Bambuterol was shown to be more cost-effective than salmeterol in patients with nocturnal asthma. The cost of the study and rescue medication was lower in all three countries in which the study was conducted (UK, Italy, and Norway) during treatment with bambuterol compared with salmeterol (mean cost of bambuterol: $0.71/day and of salmeterol: $1.15/day). |
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