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Bambec (bambuterol). Oral solution and tablets for children. A monograph 1997, ISBN 1859390633.

Bone MF, Banham SW, Joshi RC, et al. Bambuterol and theophylline: differences in efficacy, tolerability in the treatment of chronic asthma. Eur Respir J 1995; 8 (Suppl.19): 72S.

Crompton GK, Ayres J, Basran G, et al. Comparison of oral bambuterol and inhaled salmeterol in patients with symptomatic asthma and using inhaled corticosteroids. Am J Respir Crit Care Med 1999; 159: 824-8.

D'Alonzo GE, Smolensky MH, Feldman S, et al. Bambuterol in the treatment of asthma - a placebo-controlled comparison of once-daily morning vs. evening administration. Chest 1995; 107: 406-12.

Fleetham J, Grossman R, Knight A, et al. Bambuterol reduces the diurnal variation of peak expiratory flow rates in asthmatic patients. Eur Respir J 1991; 4 (Suppl.14): 480S.

Gunn SD, Ayres JG, McConchie SM. Comparison of the efficacy, tolerability and patient acceptability of once-daily bambuteroltablets against twice-daily controlled release salbutamol in nocturnal asthma. ACROBATICS Research Group. Eur J Clin Pharmacol 1995; 48: 23-8.

Knight A, Aoki F, Grossman R, et al. Bambuterol: a long-acting beta2-agonist.A dose finding study in elderly COPD patients. Eur Respir J 1990; 3 (Suppl.10): 321s.

Kuusela A-L, Marenk M, Sandahl G, et al. A comparative study with bambuterol oral solution once daily and terbutaline oral solution three times daily in 2-5 year old children with asthma. Eur Respir J 1997; 10 (Suppl. 25): 219S-20S.

McDonald CF, Pierce RJ, Thompson PJ, et al. Comparison of oral bambuterol and terbutaline in elderly patients with chronic reversible airflow obstruction. J Asthma 1997; 34: 53-9.

Persson G, Baas A, Knight A, et al. One month treatment with the once daily oral beta 2-agonist bambuterol in asthmatic patients. Eur Respir J 1995; 8 (1): 34-9.

Persson G, Pahlm O, Gnosspelius Y. Oral bambuterol versus terbutaline in patients with asthma. Curr Ther Res 1995; 56: 457-65.

Petrie GR, Chookang JY, Hassan WU, et al. Bambuterol: effective in nocturnal asthma. Respir Med 1993; 87: 581-5.

Rosenborg J, Nyberg L. Stereoselective pharmacokinetics of terbutaline and its prodrug bambuterol. Proceeding of Second Jerusalem Conference on Pharmaceutical Sciences and Clinical Pharmacology, Jerusalem, Israel, May 24-29, 1992: p30.

Sitar DS, Warren CP, Aoki FY. Pharmacokinetics and pharmacodynamics of bambuterol, a long-acting bronchodilator pro-drug of terbutaline, in young and elderly patients with asthma. Clin Pharmacol Their 1992; 52: 297-306.

Wallaert B, Brun P, Ostinelli J, et al. A comparison of two long-acting beta-agonists, oral bambuterol and inhaled salmeterol, in the treatment of moderate to severe asthmatic patients with nocturnal symptoms. Respir Med 1999; 93 (1): 33-8.

van Harreveld AJ, Peake MD, Murciano D, et al. A 12 month safety study of bambuterol, a new once daily beta2-agonist, in patients with chronic obstructive airways disease (COAD). Eur Respir J 1990; 3 (Suppl.10): 114S.

Wempe JB, Tammeling EP, Postma DS, et al. Effects of budesonide and bambuterol on circadian variation of airway responsiveness andnocturnal symptoms of asthma. J Allergy Clin Immunol 1992; 90: 349-57.
 
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Effective bronchodilation over the full 24-hour period 
Reduces diurnal variation in lung function 
Especially effective in patients with nocturnal asthma 
Effective and well tolerated in long-term treatment 
Especially suitable for children 
Suitable for the elderly 
At least as effective as oral terbutaline (t.i.d.), CR salbutamol (b.i.d.), and CR theophylline (b.i.d.) 
At least as effective and well-tolerated as inhaled salmeterol 
A prodrug of the beta2-adrenergic agonist terbutaline 
 
Different formulations of Bambec 
Alternative names for Bambec 
Bibliography 
Prescribing information