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Bambec 10 mg or 20 mg administered once daily was well tolerated and effective in the long-term treatment of chronic reversible obstructive airways disease.

1.  van Harreveld AJ, et al. Eur Respir J 1990; 3 (Suppl. 10): 114S 
 
2.  Data on file, AstraZeneca 





1. van Harreveld AJ, et al. Eur Respir J 1990; 3 (Suppl. 10): 114S
 
Over a period of 12 months, Bambec 20 mg (reduced to 10 mg if necessary) once daily had a marked beneficial effect on lung function parameters in patients with chronic reversible obstructive airways disease. Bambec was well tolerated.

Long-term Bambec treatment improves lung function in patients with asthma or reversible COPD

Mean (± SD) FEV1 in patients with chronic reversible obstructive airway disease who completed 1 year’s treatment with Bambec 10 mg (n = 10) or 20 mg (n = 95), once daily. Statistically significant improvements in pulmonary function (FEV1, FVC, and PEF) were demonstrated throughout the year.
Adapted from van Harreveld et al., 1990.
 
2. Data on file, AstraZeneca
 
The efficacy and safety record of Bambec were confirmed in the 54-month follow-up study, during which time 24 patients from the previous study (van Harreveld et al. Eur Resp J 1990; 3 (Suppl. 10): 114S) continued with Bambec therapy.

Bambec shows long-term efficacy

After a 1-month run-in period, patients received Bambec 10 mg tablets for 1 week, followed by 20 mg tablets thereafter. Compared with baseline, FEV1 was increased at almost all visits.
Data on file, AstraZeneca.
 
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Effective bronchodilation over the full 24-hour period 
Reduces diurnal variation in lung function 
Especially effective in patients with nocturnal asthma 
Effective and well tolerated in long-term treatment 
Especially suitable for children 
Suitable for the elderly 
At least as effective as oral terbutaline (t.i.d.), CR salbutamol (b.i.d.), and CR theophylline (b.i.d.) 
At least as effective and well-tolerated as inhaled salmeterol 
A prodrug of the beta2-adrenergic agonist terbutaline 
 
Different formulations of Bambec 
Alternative names for Bambec 
Bibliography 
Prescribing information